Which of the following reasons does not explain why developing resistance to vaccines less likely to occur than developing resistance to antimicrobial drugs?
A. The host immune response induced by a vaccine targets pathogens more rapidly than antimicrobial drugs.
B. Pre-transmission clearance of the pathogen from a vaccine limits the selection of partially resistant mutations that could be spread to other individuals.
C. The prophylactic activity of vaccines limits the accumulation of resistance mutatiopns prior to clearance by the immune system.
D. The mosaic-like effect of vaccines limits the liklihood that resistance in one individual would be effective in another individual during pathogen transmission.
E. Many vaccines contain multiple targets which minimizes the liklihood that a pathogen will develop resistance to each target simultaneously in a host.