The 'transforming principle' is due to the fact that DNA transferred from non-living cells to living cells could alter the features of living cells. Avery observed it by isolating and transferring the DNA of one bacterium to another.
- Griffith’s tested different biomolecules and observed that the transforming agent was DNA.
- This 'transforming principle' could alter the features of living cells when DNA was transferred from non-living cells to living cells.
- The Avery–MacLeod–McCarty experiment demonstrated that the isolation and transference of the DNA of one bacterium to another could transform the last strain, thereby concluding the genetic material of the cell is DNA instead of protein.
In conclusion, the 'transforming principle' is due to the fact that DNA transferred from non-living cells to living cells could alter the features of living cells. Avery observed it by isolating and transferring the DNA of one bacterium to another.
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