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The RNA interference is a mechanism of gene regulation in eukaryotes. Arrange the steps by which RNAi carries out gene regulation in the correct order.

1. Two strands of the double-stranded siRNA are separated.
2. One strand siRNA forms RNAse complex.
3. dsRNA cleaves to form small interfering (siRNA).
4. RNase complex binds to specific mRNA and degrades it.

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TheSandman1337
There is a mechanism of the cells that helps destroy foreign RNA, for example viral RNA. If the RNA is double stranded, a protein called Dicer cleaves the dsRNA to form siRNA (3), small RNA of lenght around 23 nucleotides. Then, the two strands of the siRNA are separated (1). Afterwards, one strand forms the RNA complex that is called RISC (2). The final step is (4); the complex attaches to a duplicate of the strand that was discarded and destroys it. Then, it is free to attach to another foreign RNA and continue its function.

1.  The enzyme dicer cleaves dsRNA to form

small interfering RNA (siRNA).

2.  The siRNA binds to a special protein,  

which degrades one strand.

3. One strand of siRNA associates with the

protein to form an RNase complex.

4. The RNase complex binds to a specific

mRNA and degrades it.  

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