First, go ahead and set it up:
[tex]4x-9-(10x+5)[/tex]
Now since you're subtracting that whole term, you must change the signs:
[tex]4x-9-10x-5[/tex]
And now you simplify:
[tex]-14-6x[/tex]
Then you can take out a -2 if you want:
[tex]-2(7+3x)[/tex]
And that's your final answer!