The effect of the poison is to make the ligase enzyme stops working.
We can arrive at this answer because:
We can conclude that the poison acted at this point in DNA replication, preventing the ligase from joining the two strands and causing the new strand to fail to adhere and was lost during the process.
The question above is incomplete, but its full version can be seen in the figure below.
More info:
https://brainly.com/question/10617612?referrer=searchResults