The types of molecules lack hydrophilic domains is option A and option D
The following information should be considered:
- Cholesterol molecules lack hydrophilic domains since Cholesterol molecules are oriented with their small hydrophilic hydroxyl group to- ward the membrane surface and the remainder of the molecule embedded in the lipid bilayer.
- Transmembrane protein are also highly hydrophobic and aggregate and precipitate in water.
- Hence option a and d are correct.
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