Adenosine triphosphate (ATP) is the fuel for muscle contraction. In muscle cells, ATP is used for the active transport of calcium ions (Ca2+) and the movement of motor proteins.
- The condition of skeletal muscle fatigue can be best explained by insufficient intracellular quantities of ATP due to excessive consumption.
- Muscle cells contain a high amount of mitochondria because they need to create more ATP to function than other cells.
- During skeletal muscle fatigue, ATP is resynthesized by the oxidation of carbohydrates and the anaerobic use of phosphocreatine.
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