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Aspirin was formed to reduce the irritation of salicylic acid. However, aspirin can still disturb the stomach. Which functional group in aspirin is responsible for stomach irritation? A. Ketone B. Ester C. Carboxylic acid D. Phenol

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Answer:

Carboxylic acid

Explanation:

Asprin is a drug that contains the carboxylic acid functional group (R-COOH), ester functional group (R-O-CO-R') and the aromatic group (benzene ring).

When we take in aspirin, it becomes salicylic acid. This metabolite irreversibly inhibits the enzyme cyclooxygenase. Hence the the production of protective prostaglandins is blocked causing inflammation and pain.

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