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Which of the following medication decrease the hepatic production of glucose?a) Biguanidesb) Meglitinidesc) Alpha-glucosidase inhibitorsd) Sulfonylureas

Respuesta :

Answer: a) Biguanides

Explanation:

It is known that the patients of type 2 diabetes mellitus are characterized by insulin resistance. It is characterized by the decrease in insulin levels by the insulin mediated glucose uptake by the peripheral tissues. This is also responsible for the increase in rate of haptic glucose production.

Biguanides are used to slow down the increasing rates of hepatic gluconeogenesis. This is done by inhibiting the two key enzymes of hepatic gluconeogenesis.

Answer:

a) Biguanides

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