Protein structure change due to many factors, change in pH and temperature can cause change in the structure of the protein.
Change in structure of the protein
- PH- decreasing the pH by adding acid, the structure of protein unfold. too much increase in the pH can denature the protein.
- Temperature- Too much temperature or heat denature the protein by destroying the non-covalent bond.
- Some other factors are hydrogen bonding, hydrophobic affect, salt bridges, vander waals force etc.
Thus, factors such a temperature, pH, solvation, primary and secondary structures etc.
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