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Gene maps represent the distribution of loci in a genome. A variety of techniques are used to construct gene maps because gene maps of organisms with large genomes are typically constructed by piecing together genome components. In particular, physical mapping approaches provide high resolution and accuracy by using molecular biology techniques. Select the physical mapping methods. somatic cell hybridization linkage analysis DNA sequencing in situ hybridization

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annyksl

Answer:

somatic cell hybridization  

in situ hybridization

Explanation:

Human genome mapping means the location of genes on chromosomes and the knowledge of the physical and genetic distances that separate them, as well as the DNA sequencing of each chromosome. The two main types of maps of the human genome are the genetic and the physical.

Physical maps derive mainly from measurements of DNA molecules and can be considered low resolution, such as cytogenetic based on chromosomal bands, or high resolution, such as restriction sites and DNA sequencing. The main physical maps are: somatic cell hybridization, radiation hybridization and in situ hybridization.

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