The mitotic spindle consists of two types of microtubules: kinetochore microtubules and nonkinetochore microtubules. In animal cells, these two types of microtubules function differently in the stages of mitosis.

Complete the sentences by dragging the labels to the appropriate locations. Labels may be used once, more than once, or not at all.

OPTIONS: Shorten, Lengthen, Disassemble
1) During prophase, the microtubules of the mitotic spindle____.

2) During anaphase, the nonkinetochore microtubules _ and move past each other, and the kinetochore microtubules.

3) During telophase, the nonkinetochore microtubules.

1. During prophase: all types of microtubules grow out at their positive(+) ends which functions to pull and push the sister chromatids apart towards opposite poles so they lengthen.

2. During anaphase : non-kinetochore microtubules- polar microtubules polymerization takes place at their (+) ends which causes the spindle fibres to move apart while kinetochore microtubules which have been attached to the kinetochores of chromosomes shorten at their (+) ends and motor proteins travel to (-) end because of which sister chromatids move towards the spindle poles.

3. During telophase: non-kinetochore microtubules depolymerize or disassembles.

Thus, 1. Lengthen, 2. Lengthen, shortens and 3. Disassemble are the correct options.