Answer:
The correct answer is option B.
Explanation:
Concentration of a steady-state plasma ,= 25 mg/L
Weight of the volunteer =75 kg
Rate of infusion = 7.5 mg/kg hr
Concentration of steady-state plasma in 75 kg weight body:
[tex]7.5 mg/kg hr\times 75 kg=562.5 mg/hr[/tex]
Total body clearance of this drug:
[tex]\frac{562.5 mg/hr}{25 mg/L}=22.5 L/hr[/tex]
The total body clearance of this drug is 22.5 L/hr.
