Nonsense mutation: changes an amino acid to a STOP codon, resulting in premature termination of translation. ... “Silent” mutation: does not change an amino acid, but in some cases can still have a phenotypic effect, e.g., by speeding up or slowing down protein synthesis, or by affecting splicing.For example, some mutations alter a gene's DNA sequence but do not change the function of the protein made by the gene. Often, gene mutations that could cause a genetic disorder are repaired by certain enzymes before the gene is expressed and an altered protein is produced.
