let's firstly convert the mixed fraction to "improper" and then proceed,
[tex]\bf \stackrel{mixed}{16\frac{2}{3}}\implies \cfrac{16\cdot 3+2}{3}\implies \stackrel{improper}{\cfrac{50}{3}}\\\\
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-18\cdot \cfrac{50}{3}\implies \cfrac{-18\cdot 50}{3}\implies \cfrac{-18}{3}\cdot 50\implies -6\cdot 50\implies -300
\\\\\\
\cfrac{-300}{1}\implies -300\frac{1}{1}[/tex]
