Which pathophysiological condition, associated with the urinary system, can affect the kidney's ability to concentrate urine and which nephron area is affected first?
a) Glomerulonephritis; proximal convoluted tubule
b) Diabetes mellitus; distal convoluted tubule
c) Renal failure; loop of Henle
d) Urinary tract infection; collecting duct
e) Renal calculi; Bowman's capsule