As part of their annual health maintenance visit, a patient screens positive for depression when the nurse administered the PHQ-2. Your preceptor asks you to interview the patient regarding the possible diagnosis of major depressive disorder. You choose to use the SIG-E-CAPS mnemonic to guide your interview. Match the letter of "SIG E CAPS" to the proper symptom of depression. For the two S's, you must use the order as indicated in the white book.

a) Sleep disturbance
b) Interest or pleasure loss
c) Guilt or worthlessness
d) Energy loss