Shown below is a model of the molecule malonyl-CoA. Use this model to complete the following tasks.
H₂N
N
NHQ
Phosphate
N
OH
O=P-OH
O
O
Methyl
OH OH
P
11
O
P
#1
O
OH
Carboxyl
ZH
N
1. In class we discussed how functional groups can determine the properties of biomolecules and how
they interact with their environment. In the boxes below, indicate whether the following groups are acidic
(A), basic (B), polar uncharged (P), or nonpolar (N).
Hydroxyl
ZH
4. How many acidic functional groups are present in malonyl-CoA?
LOH
Amino
O
2. Circle and label one example of each of these 5 groups on the figure of malonyl-CoA
3. Based on the structure of malonyl-CoA, would you expect it to be: Hydrophobic O or Hydrophilic O
5. How many basic functional groups are present in malonyl-CoA?
6. Would you expect malonyl-CoA to be able to move through a membrane using simple diffusion? Why
or why not?