G.T. is a 5-year-old white boy (weight 21.6 kg) with a medical history significant for hypoplastic left heart syndrome and recurrent otitis media. He presents after two surgical procedures to correct the congenital heart defect and is admitted today for his third procedure (Fontan) His medications are as follows: furosemide 10 mg orally twice daily and chlorothiazide 25 mg orally twice daily. He is allergic to amoxicillin (urticaria)
During the Fontan procedure, G.T. had difficulty being transitioned off cardiopulmonary bypass. Therefore, the surgery took 6 hours rather than 3 hours. Which best describes when the antibiotic should be re-dosed intraoperatively in this patient?
a. Does not need to be re-dosed.
b. 2 hours after initial preoperative dose.
c. 4 hours after initial preoperative dose.
d. 6 hours after initial preoperative dose.