G.T. is a 5-year-old white boy (weight 21.6 kg) with a medical history significant for hypoplastic left heart syndrome and recurrent otitis media. He presents after two surgical procedures to correct the congenital heart defect and is admitted today for his third procedure (Fontan) His medications are as follows: furosemide 10 mg orally twice daily and chlorothiazide 25 mg orally twice daily. He is allergic to amoxicillin (urticaria)
Which surgical prophylactic strategy is most appropriate for G.T. before his surgery?
a. Administer cefazolin 650 mg intravenously within 60 minutes of first incision.
b. Administer cefoxitin 650 mg intravenously within 60 minutes of first incision.
c. Administer clindamycin 220 mg intravenously within 120 minutes of first incision.
d. Administer vancomycin 320 mg intravenously within 120 minutes of first incision.