A previously healthy 20-year-old man presents to the emergency department assisted by his roommates. The patient is febrile, disoriented, has difficulty speaking, and is complaining of generalized abdominal pain. He has a rash that does not blanch on palpation. Laboratory findings include hematocrit 21%, platelets 10,000/mcL, MCV 90 fL, INR 1.6, and creatinine 4.75 mg/dL. Which of the following is the most appropriate next step in management?
A.Begin emergent plasma exchange
B.Hold treatment until labs for ADAMTS13 deficiency are completed
C.Prescribe cortisone cream and have the patient follow up with their primary care provider
D.Watchful waiting as the condition is self-limiting

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