Hallmarks of this type of anemia:
-formation of a fusion protein, AML1-ETO or RUNX1-RUNX1T1, due to a translocation of chromosome 8 to chromosome 21 or t(8;21):
-acute myeloid leukemia (AML)
-chronic lymphocytic leukemia
-acute promyelocytic leukemia (APL)

Q&A Education