First and second trimester findings in Down syndrome (21) include:
a) Increased nuchal translucency, absent nasal bone, and hypoplastic nasal bone
b) Cystic hygroma, rocker-bottom feet, clenched hands
c) Strawberry-shaped skull, micrognathia, low-set ears
d) Choroid plexus cysts, hypoplastic middle phalanx of the fifth digit, clinodactyly