A 1-week-old boy born at full term to a 16-year-old primigravida mother with no complications presents to the ED for lethargy. In the ED, his vital signs are T 37°C, HR 166, RR 82, and pulse oximetry of 80%. On exam, he is lethargic with diffuse pulmonary rales and rhonchi, cold extremity, and decreased peripheral pulses. Given concern for ductal-dependent cardiac lesion, you administer prostaglandin E1 (PGE1) infusion. Which of the following is a known adverse reaction of a PGE1 infusion?
-Apnea
-Hypertension
-Hypothermia
-Thrombocytosis