When considering a simplification of a 3-drug antiretroviral regimen to a 2-drug regimen of dolutegravir-rilpivirine, which one of the following is considered a requirement?

A) Virologic suppression for at least 6 months prior to the switch
B) An HIV RNA level prior to starting therapy of less than 100,000 copies/mL
C) Hemoglobin A1c less than 6.0%
D) Creatinine clearance greater than 70 mL/min